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KMID : 0356919940270070792
Korean Journal of Anesthesiology
1994 Volume.27 No. 7 p.792 ~ p.799
The Effect of Epidural Fentanyl Citrate on Epidural Morphine Sulfate Analgesia during Cesarenan Delivery


Abstract
The rapid onset of epidural fentanyl could be used to cover the latency period of epidural morphine, thus potentiating analgesia during anesthesia regression after short acting local anesthetics and possibly extending the morphine analgesia for
longer
duration. The study was designed to determine whether epidural fentanyl given before epidural morphine improves the quality of intraoperative epidural anesthesia without worsening postoperative analgesia provided by epidural morphine. Epidural
anesthesia was established using 2% lidocaine with epinephrine 5§¶/ml. Patients scheduled for study was assigned to two groups (n=20 for each). Group 1 receiving epidural normal saline-control 10 ml, and Group 2 receiving epidural fentanyl
100§¶(10§¶/ml) through epidural catheter after delivery. After uterine repair epidural morphine 10 ml 90.3 mg/ml) was injected through epidural catheter. Patients were surveyed regarding their impression on intraoperative analgesia, nausea and
postoperative analgesia, vomiting, pruritis, sedation. No significant difference was found in the two groups for intraoperative analgesia, nausea and vomiting. Postoperatively, visula analogue score for pain, vomiting, pruritis, sedation were
similar at
1,2,4,8 hours in the two groups. In conclusion, epidural fentanyl 100 §¶after delivery did not improve the intraoperative pain, nausea and early postoperative pain.
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